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This level can be met through diet alone or with a prenatal vitamin

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For patients who have difficulty absorbing B12 through the digestive tractsuch as those with pernicious anemia, gastrointestinal disorders (like Crohns disease or celiac disease), a history of gastric bypass surgery, or those with severe B12 deficiencyour providers often recommend intramuscular B12 injections

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Chromatin status is driven by the activity and level of chromatin-modifying enzymes such as DNA methyltransferases (DNMT) and histone deacetylases (HDAC) (90) ( Figure 2 )

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