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It is important to carefully determine the types of antimicrobials to be used as many antibiotics and antivirals can have negative adverse reactions (Mohsen et al., 2020

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doi: 10.1016/j.clim.2014.03.014

Nevertheless, evidence is still lacking to determine the optimal scaffold composition that meets the specific requirements and complexities needed to effectively promote tissue engineering of cells in the oral cavity [63]

Furthermore, the results are not always predictable as HA gels are extremely hydrophilic, meaning they can absorb a lot of water
