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To further determine if the early changes in peptide/protein abundance are related to the change in C-peptide in the longer term, the trends in peptide levels during the first year were compared with the fasting C-peptide/glucose ratios at 24 months

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As showed in Figure 3A, IRE1, GRP78, XBP-1 and CHOP were increased significantly after TBI injury, and reversed following the 3-day treatment of vitamin B12

doi: 10.1001/jamainternmed.2022.6555 177 WangM.LkhagvaE.KimS.ZhaiC.IslamM

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