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For example, naringenin, an active metabolite found in tomatoes, grapefruits, and oranges, can inhibit the proliferation and migration, and induce apoptosis of BCSCs by regulating the transforming growth factor- (TGF-) and Wnt/-catenin pathways in MCF-7 cells

doi: 10.1016/j.ijbiomac.2021.10.068 111

Early metformin in gestational diabetes: a randomized clinical trial

DTP cells, which emerge as a result of cancer cells undergoing specialized adaptations in response to drug exposure, represent a distinct subgroup of cancer cells that exhibit pivotal non-genetic characteristics in comparison with those seen in various cancer cell lineages

Yes, under clinical supervision

The RGD-(KLAKLAK)2 and NGR-(KLAKLAK)2 were especially toxic to angiogenic endothelial cells leading to reduced tumor growth and metastases as well as prolonged survival