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found no beneficial effects of long-term allopurinol treatment on cardiovascular mortality

Therapeutic Use of Nicergoline

In three of these studies, penile curvature was also analyzed and was always significantly reduced at the post-treatment controls

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The TMAO levels are also elevated in patients with chronic HF, correlating with the functional class and diastolic dysfunction, but not systolic dysfunction, suggesting that increased venous congestion associated with backward failure may significantly alter the gut microbiota (GMB) to promote TMAO production

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