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The biology and function of exosomes in cancer

These findings highlight the renoprotective effects of TFA and EB, with their combination (TFA-EB) offering superior benefits in ameliorating DKD-associated structural and functional renal abnormalities (see Figure 2)

While both have the name glutathione peroxidase, C-Gpxs actually use thioredoxin (Trx) rather than glutathione (GSH)

MG is an organic compound that is developed under different abiotic stress conditions and cause toxicity to plants

Disulfiram (DSF) is a therapeutic substance conventionally employed to combat alcohol intoxication

GPX4, a selenocysteine-containing enzyme, utilizes GSH to reduce toxic phospholipid hydroperoxides (PL-OOHs) to non-toxic phospholipid alcohols (PL-OHs), thereby disrupting lipid peroxidation chain reactions and preventing oxidative cell injury (Pontel et al., 2022)