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Yes, studies show some lean mass reduction, but also improvements in muscle quality as fat within the muscle decreases
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6 Bedard NA, DeMik DE, Glass NA, Burnett RA, Bozic KJ, Callaghan JJ

The compound is synthesized using solid-phase peptide synthesis and purified through HPLC to ensure analytical-grade purity
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(2013) Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy
