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The multiple mechanisms that exacerbate calcium dysfunction within neurons in TBI lead to impairments in synaptic plasticity as indicated by various studies showing deficits in long term potentiation (LTP) in TBI mouse models (Sick et al., 1998

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While BPC-157 focuses on localized tissue repair and new blood vessel formation, TB-500 works systemically to regulate cellular movement and reduce inflammation across the body

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Naloxone-induced analgesia mediated by central kappa opioid system in chronic inflammatory pain