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Pickart, Vasquez-Soltero, and Margolina 2015)

Lower-dose maintenance and full discontinuation produce different outcomes

Staszkiewicz R, Gadysz D, Gralewski M, Garczarek M, Gadzieliski M, Grabarek BO

Research shows it stimulates fibroblast proliferation, supports collagen synthesis, promotes angiogenesis via VEGF pathways, modulates matrix metalloproteinase activity, and upregulates key growth factors involved in connective tissue repair

doi: 10.1128/mBio.02094-21 53 DavisD

doi:10.1002/14651858.CD013823.pub2