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A Russian brain-targeted tripeptide with an unusual proposed mechanism, a body of preclinical neuroprotection data, and a safety signal that looks mild without being stress-tested
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Subcutaneous and intraperitoneal routes achieve 6090% bioavailability, while intranasal delivery offers higher CNS-specific bioavailability (3060%) with lower systemic exposure
Humans express two thioredoxin encoding genes TXN and TXN2 with the TXN2 encoded protein being involved in the regulation of mitochondrial membrane potential
