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TGF- has been shown to inactivate Nrf2 and repress expression of various Nrf2 target genes in both mesenchymal cells and epithelial cells 56,57 , but also upregulation of antioxidant genes by TGF- has been reported 58,59

2009;5:e1000685

[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Garaci E, Palamara AT, Ciriolo MR, et al

A critical aspect of this involves their interaction with mitochondrial Complex I

doi: 10.1152/physrev.1999.79.1.S145
