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Schrag A, Trimble M, Quinn N, Bhatia K

Recently, a minimally invasive system of transdermal delivery using microneedles (MNs) has received great attention from medical practitioners, particularly for the delivery of bioactive agents such as peptides and proteins that are labile to gastrointestinal pH and susceptible to enzymatic degradation [15]

In a recent study, Deferasirox was evaluated in three distinct murine Alzheimer paradigmsTg2576 (APP-only), JNPL3 (Tau-only), and Tg2576/JNPL3 (APP + Tau)to assess its therapeutic impact

When zinc levels are low, less metallothionein is produced, potentially leading to copper overload

doi: 10.1016/j.bcab.2019.101449 29 GinwalaR.BhavsarR.ChigbuD