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Differences in spRNA transcripts among high- and low-fertility dairy bulls have been reported with 805 unique transcripts in high-fertility and 2,944 unique transcripts in the low-fertility bulls ( COX7C ) was negatively correlates with male fertility ( AK1, ITGB5, TIMP , SNRPN2 , and PLCz1 ) accounted for 97.4% of the variation of conception rate from frozen-thawed Holstein bulls, which was indicative of the sire fertility index (Kasimanickam et al., 2012)