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258,259 In senescent cells, the mitochondrial fission increases, causing the increase of dysfunctional mitochondria

doi: 10.7150/jca.82066 67 GaoCXiaoFZhangLSunYWangLLiuXet al
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In an environment of energy stress, mTORC1 becomes continuously and abnormally active, driving unnecessary protein and lipid synthesis, which exacerbates the metabolic burden on cells
