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Sometimes in cases of depigmentation, it may be difficult to differentiate vitiligo from lichen sclerosus (Fig

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[PUBMED Abstract] Taylor NJ, Reiner AS, Begg CB, et al.: Inherited variation at MC1R and ASIP and association with melanoma-specific survival

In the context of the Melanotan-1 pathway, this genotype may indicate a less responsive melanocortin signaling environment, where peptide-driven stimulation of melanin production may be somewhat attenuated

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