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An optional EDTA solution is provided for enhanced metalloprotease inhibition, and is provided separate as it would inhibit the activity of proteins that require divalent cations (Ca + , Mg + or Mn + ) for their biological activity and will inhibit the purification of proteins using immobilized metal affinity chromatography (IMAC)

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Qualified providers should evaluate comorbidities, medication interactions, and individual risk factors before recommending either approach

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