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GLY/DPI produced a higher incidence and more severe AEs of headache compared to GLY/eFlow (Table 4)
The above leads to the overproduction of ROS and RNS, and it intensifies cytokine and chemokine secretion via a positive feedback loop (174)
These results suggest that Hcy-induced hypomethylation of DNA, RNA, protein in ECs leads to endothelial injury by impairing water permeability, inducing inflammation, and inhibiting proliferation
Krishnaiah D, Sarbatly R, Nithyanandam R
Neuroscience 156, 830840
& Chance, B
