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As a modulator of the kynurenine pathway, NAC reduces kynurenic acid levels via inhibition of the KAT/AadAT enzyme in the prefrontal cortex and influences dopamine release in the striatum, potentially through GSH-mediated modulation of glutamate receptors [23, 141]

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Litvinov RI, Peshkova AD, Le Minh G, Khaertdinov NN, Evtugina NG, Sitdikova GF, Weisel JW (2021) Effects of hyperhomocysteinemia on the platelet-driven contraction of blood clots

Clinical Chemistry 1999;45(5) 593-615

Fifty microliters of samples or 8-oxoG standards were added to the wells of the 8-oxoG conjugate-coated plate and incubated for 10 min at room temperature on an orbital shaker