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Alloimmunization owing to these autobodies can sometimes cause severe hemolytic disease of the fetus requiring prenatal intervention

Lower NAD+ means reduced sirtuin activity (SIRT1, SIRT3), which further impairs mitochondrial function and fatty acid oxidation in fat cells

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3) both in epidermal keratinocytes and dermal fibroblasts, exhibits strong proinflammatory and vasodilatory properties

Contursi, A., Fullone, R., Szklanna-Koszalinska, P., Marcone, S., Lanuti, P., Taus, F., Meneguzzi, A., Turri, G., Dovizio, M., Bruno, A., Pedrazzani, C., Tacconelli, S., Marchisio, M., Ballerini, P., Minuz, P., Maguire, P., & Patrignani, P

By inhibiting activation of system Xc, the absorption of cystine is reduced and the synthesis of GSH is diminished