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Additionally, endothelial cells exposed to oxHb show rearrangement of the actin cytoskeleton leading to disruption of the endothelial cell monolayer, intercellular gap formation and increased permeability of the monolayer, which did not occur upon heme exposure (Silva et al., 2009)

Current evidence suggests that its functional outputs are markedly context-dependent

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Data were presented as mean standard error (SE) or median and inter quantile range (IQR) (25th [Q1] and 75th [Q3] percentiles) and a significant difference was considered as p 0.05)

Injuries to the left adrenal gland typically occur with trauma slightly more medial and inferior to the spleen