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In PD patients, the whole-blood GSH/GSSG ratio increased by 231% and red blood cell catalase activity by 215% (vs

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These distinguished effects may be attributed to the TME modulation capacity of H-MnO 2 -based nano-platform and the subsequently enhanced chemo-PDT treatment to induce the release of tumor-associated antigens 49, 50 , which would activate dendritic cells and then the recruitment of effector T cells into tumors

Iron is then transported in the plasma as a complex with transferrin (Tf), which is detected by transferrin receptor 1 (TfR1) or 2 (TfR2) and endocytosed as the Fe-Tf complex [12] (Figure 2)

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10.1016/j.pbb.2011.01.011 163 NagashayanaN.SankarankuttyP.NampoothiriM.MohanP.MohanakumarK