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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Jo C., Kim S., Cho S.J., Choi K.J., Yun S.M., Koh Y.H., Johnson G.V.W., Park S.I

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Together, these studies highlight the complex interplay between CKD, neuroinflammation, and gut-derived signals, providing strong evidence that the gut microbiota and its metabolites play a significant role in promoting neuroinflammatory processes in CKD, which in turn contribute to cognitive decline and neurodegenerative changes

Nutrition Reviews 2013;71(2):1107