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Starting with a conservative dose and titrating up is always the wisest approach

T1weighted imaging offers detailed anatomical views of the brain, while T2weighted imaging excels in detecting abnormalities like edema or inflammation [56, 57]

But despite all the research, outdated creatine myths around bloating, kidney damage, and water retention still put some people off

Outside controlled laboratory environments light intensity is higher, light and temperature fluctuate unpredictably in the short term, mineral nutrients and water supply vary and pests and pathogens are always present

It's really important to chat with a healthcare provider

From a preclinical perspective, attention is focused on the development and optimisation of preclinical models, to better elucidate irAE mechanisms that may tailor diagnosis and management