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In L-NAME-treated Wistar rats, NAC treatment increased NOS activity in the left ventricle and kidney (32)

Zieg (Charles University Prague, University Hospital Motol, Prague, Czech Republic), L

stimulated macrophage cell activation, leading to the upregulating of pro-inflammatory cytokines, including TNF-, IL-6, and IL-10

82 The authors showed that there was no significant difference between hyperthyroid patients and healthy subjects

This protective effect was associated with an increase in miR-146a expression and the anti-inflammatory cytokine IL-10, along with a reduction in the pro-inflammatory cytokine TNF- levels (Qu et al., 2022)