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Consensus guidelines for the diagnosis and management of pyridoxine-dependent epilepsy due to -aminoadipic semialdehyde dehydrogenase deficiency

Yang Y, Li C, Qi Z, Xiao J, Zhang Y, Yamaguchi S, et al

The medicinal form depends on how well it is absorbed in the body and factors such as age, genetics, and the condition of the digestive system
Protein sufficiency (collagen remodeling depends on amino acid availability)

Clinical trial protocols titrate gradually

Pregnant animals can transfer vitamin B12 to a growing fetus, but do not supply any of the vitamins in their milk