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A previous search, using the Connectivity Map developed by the Broad Institute, found that GHK could alleviate impairment of TGF1 signaling (Pickart et al., 2017), a pathway associated with A deposition and neurofibrillary tangle formation (Bosco et al., 2013)

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Their reviews have been published on the total synthesis of sulfur-containing natural products via introducing sulfur atoms with different sulfurization agents and constructing related sulfur-containing moieties (Wang et al

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The polyol pathway involves the reduction of glucose to sorbitol via the action of the NADPH-dependent aldose reductase encoded by the AKR1B1 (aldo-keto reductase family 1 member B) gene

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One notable innovation is AI-based organoids, which represent the convergence of AI and organoid technology

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Nature 449, U463U465

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