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doi: 10.1371/journal.pone.0066388 139 SchiavoneS.SorceS.Dubois-DauphinM.JaquetV.ColaiannaM.ZottiM.et al
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The clearest evidence to illustrate the similar physiologic functions has been shown in tumor-associated hypoglycemia induced by the pathophysiologic elevation of insulin 10, 11 or IGF-2 from islet 12 or non-islet tumor cells
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Indeed, in view of the toxic nature of free heme it seems likely that its concentration in the cytoplasm should be vanishing small
