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65,67 Corticotropin-releasing hormone activates the stress response by stimulating pituitary secretion of adrenocorticotropic hormone (ACTH), which in turn stimulates cortisol release from the adrenal glands
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However, research suggests that these side effects are uncommon
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Furthermore, several studies also showed no remarkable association between TMAO and history of CHD or incident CV events or CV mortality (Kaysen et al., 2015
