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[email protected] Specialty section : This article was submitted to Cellular and Molecular Mechanisms of Brain-aging, a section of the journal Frontiers in Aging Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Its clearance can increase due to the saturation of its transport system, particularly at high doses or with chronic supplementation because of the reported skeletal muscle store saturation [23]

The incubation period for infection ranges from 1 month to 2 years and typically microfilariae appear before overt symptoms.The accumulation of many infective mosquito bites several hundreds to thousands is required to establish infection

However, chronic GH treatment carries substantial risks, including glucose intolerance, insulin resistance, diabetes, cancer, and cardiovascular complications

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