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What is the mechanism of action of these agents

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Glutathione: the master antioxidant Antioxidants are molecules that inhibit other molecules from going through oxidation, a chemical reaction that produces toxins called free radicals

Its selective permeability, governed by tight junctions, transport proteins, and metabolic enzymes, severely restricts brain penetration of macromolecular therapeutics, necessitating high systemic doses that cause hepatotoxicity and immunosuppression