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Impurity profiling of the most frequently encountered falsified polypeptide drugs on the Belgian market
NNMT in Aging and Metabolic Disease 7.1 Obesity, Insulin Resistance, NAFLD/NASH High NNMT expression in adipose tissue correlates with obesity , insulin resistance , and progression of nonalcoholic fatty liver disease to NASH , due to decreased NAD and global methyl depletion
Whats more, children with infantile spasms had higher levels of serum homocysteine and urinary methylmalonic acid compared to the control group, suggesting a potential association between vitamin B12 deficiency and the occurrence of infantile spasms [97]
A vitamin B12 deficiency may be the cause
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