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[DOI] [PMC free article] [PubMed] [Google Scholar] Sausen de Freitas A, de Souza Prestes A, Wagner C, Haigert Sudati Js, Alves D, Oliveira Porcincula L, Kade IJ, Teixeira Rocha JoB

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GSTs also catalyze reactions with epoxide moieties (e.g., in the conversion of leukotriene A 4 (LTA 4 ) to leukotriene C 4 (LTC 4 ))

However, due to the off-target effect as a multi-kinase inhibitor [8], therapeutic advances are directed toward targeting metabolic vulnerabilities associated with SLC7A11 pathways in cancer