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491 Patients who received 200 mg of mirikizumab subcutaneously every 4 or 12 weeks presented a significant downward trend in the expression of genes encoding inflammatory mediators, such as cytokines and chemokines

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[DOI] [PMC free article] [PubMed] [Google Scholar] [64].Freedman MRC JH, Peisach J

Immune cytokine signatures of PASC patients reflect an ongoing chronic inflammation and angiogenesis with elevated plasma levels of IL-17a, stem cell factor, IL-12p70, IL-1, macrophage inflammatory protein-1 (MIP-1), brain-derived neurotrophic factor (BDNF), and VEGF 223 Also, among other immune mediators, reduced levels of cortisol strongly correlate with pulmonary-PASC symptoms 224