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The defect may be small enough to almost close at the end of a systolic decrescendo murmur

32 This dysfunction theoretically could lead to an increased vulnerability to neurotoxins following exposure to sulfur-containing substances

doi: 10.1073/pnas.2012748118 273 SunJBokRADeLos SantosJUpadhyayDDeLos SantosRAgarwalSet al

The difficulty in imaging and assessing the glycocalyx is attributable to a number of technical issues that have prevented a full characterization and understanding of its structure and function in maintaining vascular homeostasis, as well as how its degradation contributes to a myriad of different pathologies including diabetes, hypertension and inflammation

Yu 2025 Cell Metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Kim J., Hong S