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The iPSCs were further differentiated into GABA progenitors (MiPSC-iGABAPs) and subsequently transplanted into the right medial forebrain bundle of rats with 6-OHDA-induced lesions [93]
Additionally, Cys-Tyr cofactor formation increased the catalytic lifetime of CDO, with the t 1/2 for catalytic activity measured in vitro being approximately double that of the immature enzyme
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However, succinyl-CoA can also be generated through the catabolism of other amino acids, such as isoleucine, or the short-chain fatty acid propionate, produced by gut bacteria
In: J Pharm Sci
