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Alcoholism and Chronic Illness Excessive alcohol intake and some chronic conditions can reduce nutrient absorption and deplete B12 levels in the body

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Minimal Systemic Effects: Works primarily at the application site with limited whole-body exposure

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Can peptides replace physical therapy

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Surgeries Associated with B12 Deficiency: Weight Loss Surgery: Procedures such as gastric bypass can reduce the stomachs capacity and alter the digestive tract, impacting B12 absorption

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However, clinical conditions associated with high B12 are uncommon

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Inborn errors of metabolism (e.g., vitamin B6-dependent convulsions or B6-responsive anemia)

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