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Every identified direct target was exclusively upregulated when HIF-1 was active, consistent with a transcriptional activator (Fig

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Therefore, exposure to foreign antigens from the first stimulus or to EBV viral antigens leads to activation of CD4 T cells and IFN- release, provided that the cells presenting these antigens to CD4 T cells are not previously infected with EBV, since the gp42HLA-II complex in these cells would prevent their activation [171, 194]

Previous studies have assessed the role of SWI/SNF in regulating NRF2-driven targets such as SLC7A11 and HMOX1 23

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