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Astrocytes in AD model animals demonstrated up-regulated expression of genes (CPS1, OCT, ASL, ARG1, and ODC1) and metabolites (aspartate, ammonia, urea, putrescine, and GABA) of the urea cycle

Results Directly relevant to its use as a PD therapeutic is the capacity of Dihexa to act synergistically to protect neurons from general growth factor deprivation (Figure 46) and oxidative stress (Figure 47), the underlying cause of neuronal cell death in PD

doi: 10.1111/j.1471-4159.2011.07619.x 61 FangYYanJLiCZhouXYaoLPangTet al
