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5-Amino-1MQ is a small molecule that acts as a potent inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT)

However, using it alone isn't sufficient

Accurate comprehension of the WADA Prohibited List structure and scope is critical for athletes and supplement manufacturers to avoid inadvertent anti-doping rule violations and safeguard athletic eligibility and brand reputation

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In some embodiments, NNMT inhibitors may be used with one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that increase intracellular NAD+ levels, to produce synergistic or additive effects to provide muscular therapy

In people with normal absorption, deficiencies have been reported only in strict vegetarians who consume no products of animal origin (including no milk products or eggs)