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Amides That Are Unusually Easy To Break (2) Beta-Lactams As described in The Enchanted Ring , MIT chemist John Sheehan and his research group had a hell of a time synthesizing penicillin

Assessment of reactivity of 2 and TRi-1 with N-Boc protected methyl ester of L-selenocysteine Dimethyl bis( N - tert -butoxycarbonyl)-L-selenocystine was synthesized as reported previously 85
The reaction is mediated by glutaminase and can be displayed as: Glutamine + H 2 O Glutamate + NH 3

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