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Sensitivity or Allergies to B12 or Its Components: Some individuals may have an allergic reaction to the preservatives or additives in B12 injections, especially those with known sensitivities to certain medications or substances

Prescription drug prices, including Vitamin B12 Injection, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations

doi: 10.1073/pnas.171325998

This has been explored by clinical trials, the most notable of which was METAOD005

Seif et al., 2010)

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