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doi: 10.1159/000484679

doi: 10.1073/pnas.76.11.5684
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The disease manifests with neurologic symptoms in a relapsing-remitting (RRMS) as well as a primary (PPMS) or secondary progressive (SPMS) form

The role of succinate in the regulation of intestinal inflammation

Overall, this work highlights the involvement of Fabp5 in Ps pathogenesis and provides convincing evidence that systemic interventions, targeting Fabp proteins and ferroptosis, mimicking the effect of BMS/Lip-1 and/or preventing lipid peroxidation by restoring Gpx4 expression, might still be of interest to potentiate current therapies targeting skin manifestations in Ps