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Description
10.1073/pnas.90.23.11217 Proc
All-in-one care for skin brightening, wrinkle improvement, and hydration
Arthritis Res Ther (2015) 17:302
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Plots on the Supplementary Fig
This peroxidation occurs via two major pathways: the enzymatic pathway, mediated by lipoxygenases (LOXs), cytochrome P450 oxidoreductase (POR), and NADPH oxidases (NOXs), promotes the generation of PUFA-PL-OOHs, leading to the accumulation of reactive aldehydes, ketones, and other toxic metabolites, ultimately disrupting membrane integrity and triggering ferroptosis (Maheshwari, 2023)
