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Moreover, as lysosomal function is essential for mitophagy, impairment in the fusion of lysosomes with autophagosomes-containing mitochondria may compromise the clearance of dysfunctional mitochondria, resulting in exacerbated APAP hepatotoxicity

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Structure and mechanism of human cystine exporter cystinosin

IBD in Cats While they sound similar, Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS) are different conditions

doi: 10.1007/s11095-009-9964-5

The role of the gut as a mediator is unequivocally demonstrated in models of chronic apical periodontitis (CAP), where P.g -induced CAP alters gut microbiota (increasing Lachnospiraceae , Ruminococcaceae ) and increases TMAO, thereby exacerbating aortic plaque formation