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It can be improved within 1-2 weeks, whereas some chronic diseases, such as arthritis or tissue regeneration, can require 4-6 weeks or more

No serious adverse effects have been reported in clinical studies

doi: 10.1093/eurheartj/ehv140

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5 Electrophysiological investigations, including EEG and event-related potentials (ERPs), have indicated differences in attention-related brain network activity and cortical arousal
