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When these drop below the ideal value the hypothalamus is signaled to begin secreting thyroid-releasing hormone again
Under normal conditions, activated Met is rapidly removed from the cell surface by ubiquitination, and then targets the lysosomal degradation chamber
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Ortiz-Meoz RF, Jiang J, Lazarus MB, Orman M, Janetzko J, Fan C, et al
Politis 2014)
