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Journal of Physiology, Paris , 87 (5), 313327

Substances in the periphery appear to make the DRGs behave differently, such that the signals entering the spinal cord are chronically amplified

These signals include changes in metabolite concentration, hormone signals, and oxidative stress

This is also why you might notice that diets and exercises that worked for you in the past do not work as well or at all later in life

| Emily Kaplan

Peters et al., 2011
