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Discovery of 6-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity

Research shows that diets enriched with pure MCTs lead to greater weight reduction compared with diets containing long-chain fats, with particular benefits for individuals who are overweight or obese

Furthermore, as a cyto-protectant, melatonin helps alleviate several COVID-19 comorbidities, including T2DM, metabolic syndromes, and both ischemic as well as non-ischemic CVD 657