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Moreover, we further identified P300 as the main succinylation-catalyzing enzyme of GCLC, and their association showed a remarkable decrease upon ROS treatment

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DOI: 10.1016/j.antiviral.2009.04.010 42

Further, we discuss the potential contribution of additional sources of cysteine to the cysteine pool and what is known about the essentiality of these processes in cancer cells

Despite substantial inter-individual variability, the model accurately captured population-level pharmacokinetic diversity and provided reliable risk assessments