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The ratio of eumelanin to pheomelanin is genetically determined by a number of factors including the degree of base-line functional activity of the enzymes and proteins driving the mixed melanogenesis, by the melanocortin 1 receptor (MC1R) genetic polymorphism, and by the amount of the tyrosine in the melanosome [6]

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[Abstract]2026 Jun 15

As a result, multiple studies show that obese people have elevated non-HDL-C levels and that weight loss reduces non-HDL-C [14, 15, 16, 17]

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